Laboratory Technologist / Senior Laboratory Technologist

Xilis, Inc. is an innovation-driven biotech company developing its proprietary MicroOrganoSphere (“MOS”) Technology for functional precision oncology. Xilis’ MOS Technology enables rapid and scalable generation of patient tumor models that retain patient-specific tumor biology and tumor microenvironment, representing one of the most translationally-relevant ex vivo technologies for precision oncology drug discovery and development. Located in Research Triangle Park, Durham, NC, Xilis is building a functional precision medicine platform that incorporates scaled multi-modal profiling of therapeutic activity and AI/ML-enabled analytics to catalyze functional precision medicine drug discovery, development and diagnostics. Collectively, Xilis aims to harness its MOS Platform to enable development of the most effective therapeutics and guide them to the right patients at the right time.

Role

The candidate will perform patient specimen testing procedures in accordance with SOPs and CLIA regulatory guidelines and help to streamline laboratory processes. This will include performing end-to-end laboratory processes including cell and tissue culture techniques, cell-based microscopy and imaging, and operation of critical laboratory equipment. The successful candidate will bring exceptional skills and abilities to the laboratory. The candidate will also have strong attention to detail and the integrity to precisely document and report any deviation or issue observed in the laboratory. Finally, the candidate’s communication skills will be stellar. The candidate will report to Xilis’ Manager of Diagnostic Laboratory Operations.

• Participate in all phases of clinical and biological sample testing procedures.
• Perform routine equipment maintenance and cleaning
• Assist with the improvement of Standard Operating Procedures (SOPs)
• Work closely with the assay development, operations, and quality teams to develop and maintain quality assurance (QA) and quality control (QC) protocols
• Identify and document potential QC or processing issues and report to management
• Operate successfully in a fast-paced, mission-driven environment
• Share thoughts and ideas on how to improve performance in the lab
• Perform support tasks across the team as needed

• B.S. or M.S. degree in biology, molecular biology, biomedical engineering, biotechnology, or equivalent
• 2+ (5+ years for senior level) of experience in a laboratory environment, preferably in a CLIA diagnostic testing environment
• Hands-on laboratory experience in sample processing, cell culture, and lab automation
• Experience with 3D cell culture and flow cytometry strongly preferred
• Experience working cross-functionally, demonstrated exceptional written and verbal communication skills
• A strong sense of commitment, integrity, and handling challenges collaboratively
• Experience and interest in a high-growth startup is preferred

Xilis was created when its three founders — an engineer, a physician, and a biologist — decided to come together and commercialize their technology to transform cancer care. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. We do not discriminate on the basis of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or Veteran status. Furthermore, even if your work experience isn't perfectly aligned with what we've described above, if you're excited about what we're building then we want to talk to you!

Xilis offers comprehensive health, vision, dental & retirement plans, and unlimited PTO. We are a remote-friendly team: our headquarters are in Durham, North Carolina, but we have team members across the US (and beyond!).