Experience level: Masters, PhD or equivalent work experience
The position
We are currently looking to hire an exceptionally skilled and hard-working AS/Scientist with 3+ years of experience in mouse iPSCs culture and differentiation protocols to join our R&D team. You will work differentiating mouse iPSCs into functional end-cell types, optimizing existing protocols, and developing new differentiation protocols. You will be part of a team developing and optimizing mouse in vitro gametogenesis protocols (Hikabe et al., 2016; Hayashi et al., 2017; Yoshino et al., 2021) to generate a mouse pre-clinical data package. This work will contribute to safety studies needed to advance human in vitro gametogenesis into clinical applications.
Our mission
Conception is a startup with the mission of generating viable human eggs from induced pluripotent stem cells (iPSCs). Successful development of our research could have many benefits, such as removing age limits on motherhood, allowing for easy screening of eggs with harmful genetic mutations, and allowing same-sex couples to reproduce.
What we are looking for
As a mouse iPSC expert, you will help with iPSC line generation and characterization, iPSC maintenance, quality control, troubleshooting, and clonal line generation. You will also help troubleshoot a variety of iPSC differentiation protocols to induce germ and somatic ovarian cells. Eventually, your role could also include working with 3D organoids and generating reporter cell lines and using CRISPR-based gene editing tools. You will contribute to designing and executing critical data for the mouse pre-clinical safety package, including exposure to regulatory strategy planning.
Come and work with us
We are well-funded and connected in Silicon Valley, offering:
Competitive salary and company equity.
Comprehensive healthcare benefits.
A focused and supportive research environment committed to achieving impactful results
Expertise in mouse iPSC cultures is required. Other valuable experience includes iPSC differentiation protocols, cell sorting, gene editing and interpretation of computational data (e.g., SmartSeq2, Single-Cell RNA-seq). We can provide training in areas of inexperience if you are passionate about our goal.
Mission alignment, as well as a solid scientific background with a reliable track record in executing experiments, is something we strongly care about. You will work closely with other project teams and should be a great communicator, maintain detailed and accurate records, and have an eye for detail.
If you are passionate, hardworking, and aligned with our mission, we want to hear from you.
To learn more about the original mouse proof of concept to live birth that inspired us, see https://www.nature.com/articles/nature20104
To learn more about us, our mission, and approach you can read two features published by The New Yorker and MIT Technology Review.
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Are you an innovative mind with a passion for stem cell research? We invite you to join Conception as our new Associate Stem Cell Scientist in Berkeley! With at least 3+ years of experience in mouse iPSCs culture and differentiation protocols, you'll be at the forefront of groundbreaking research that could transform reproductive science. In this role, you will work on differentiating mouse iPSCs into functional end-cell types and optimize protocols. You'll also contribute to developing critical in vitro gametogenesis processes that hold promise for advancing human reproductive techniques. As part of a vibrant R&D team, you'll engage in exciting projects aimed at generating viable human eggs from iPSCs, potentially changing the future of motherhood, allowing screening for genetic mutations, and enabling same-sex couples to have children. If you have the expertise in iPSC generation, quality control, and differentiation protocols, as well as familiarity with gene editing tools like CRISPR, we’d love to hear from you! At Conception, you will enjoy competitive salary packages, equity options, and comprehensive healthcare benefits, all within a supportive research environment that values collaboration and innovation. If you're enthusiastic and ready to dive into impactful research, don't miss this opportunity to make a difference in the field.
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