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Senior Program Manager - Innovation Research

GeneDx (Nasdaq: WGS) delivers personalized and actionable health insights to inform diagnosis, direct treatment, and improve drug discovery. The company is uniquely positioned to accelerate the use of genomic and large-scale clinical information to enable precision medicine as the standard of care. GeneDx is at the forefront of transforming healthcare through its industry-leading exome and genome testing and interpretation services, fueled by the world’s largest, rare disease data sets. For more information, please visit www.genedx.com.

The mission of the Innovation Lab is to increase the diagnostic yield of our exome and genome products and reduce the time to diagnosis for patients with undiagnosed hereditary disease. Our vision is to deliver personalized and actionable health insights to every person who orders a genetic test from GeneDx. Achievement of our goals will require a culture of innovation, where creativity, experimentation, and the pursuit of new ideas are encouraged and embraced. Individuals are empowered to think critically, take risks, and challenge the status quo, to generate breakthrough solutions and drive positive change.

Summary:

We are looking for a driven, experienced, and hands-on Senior Research Program Manager to turn ideas into reality - managing early-stage research projects, validating approaches, and guiding them to scalable production. You will own the project pipeline, bridge the gap between teams, drive execution, and contribute ideas and solutions for what we should pursue next—both strategically and tactically.

  • Program Project Management: Plan, organize, and manage multiple research projects from inception to completion, ensuring they meet timelines and quality standards.
  • Team Coordination: Coordinate cross-functional teams, including genomic researchers, data scientists, bioinformaticians, genetic counselors and medical geneticists, fostering effective collaboration and communication.
  • Budget Management: Maintain budgets for research programs, including financial planning, tracking, and reporting.
  • Risk Management: Identify potential risks for genomic research projects and develop mitigation strategies to ensure successful outcomes.
  • Compliance: Ensure all research activities comply with LDT and FDA regulatory requirements, ethical standards, and organizational policies in collaboration with quality department.
  • Stakeholder Communication: Maintain effective communication with stakeholders, including senior leadership, product owners, software developers and lab directors, providing regular updates and reports.
  • Performance Tracking: Monitor project progress and performance, using metrics and data to evaluate success and identify areas for improvement.
  • Documentation: Ensure thorough documentation of research processes, SOPs, findings, and outcomes, maintaining accurate and comprehensive records.
  • Innovation: Using your expertise in genetics and program management, d Drive innovation in diagnostic testing, analysis and interpretation through genomic research projects and transfer into the commercial laboratory.
  • Individual contribution: Contribute to data analytics, genetic interpretation and/or the evaluation of software tools for clinical genomic analysis and research, approximately 20% time.

People Manager:

  • No

Education, Experience, and Skills:

  • Education: Advanced degree (preferably PhD) in a relevant field such as Genetics, Genomics, Biotechnology, or related discipline.
  • Experience: Extensive experience in genomic research and/or program management, preferably within the diagnostic, biotech or life sciences industry, 8+ years.
  • Skills: Strong organizational, communication, and analytical skills, with the ability to manage complex projects and teams.
  • Technical Knowledge: Understanding of DNA & RNA sequencing technologies, bioinformatics, clinical interpretation of genomic data, and/or regulatory requirements for lab designed tests
  • Leadership: Proven ability to lead and mentor teams, fostering a collaborative and productive work environment.
  • Problem-Solving: Strong analytical and problem-solving skills, with the ability to develop innovative solutions to complex challenges.

#LI-REMOTE

Pay Transparency, Budgeted Range
$170,000$190,000 USD

~

Science - Minded, Patient - Focused. 

At GeneDx, we create, follow, and are informed by cutting-edge science. With over 20 years of expertise in diagnosing rare disorders and diseases, and pioneering work in the identification of new disease-causing genes, our commitment to genetic disease detection, discovery, and diagnosis is based on sound science and is focused on enhancing patient care.

Experts in what matters most. 

With hundreds of genetic counselors, MD/PhD scientists, and clinical and molecular genomics specialists on staff, we are the industry’s genetic testing experts and proud of it. We share the same goal as healthcare providers, patients, and families: to provide clear, accurate, and meaningful answers we all can trust.

SEQUENCING HAS THE POWER TO SOLVE DIAGNOSTIC CHALLENGES.

From sequencing to reporting and beyond, our technical and clinical experts are providing guidance every step of the way:

TECHNICAL EXPERTISE

  • High-quality testing: Our laboratory is CLIA certified and CAP accredited and most of our tests are also New York State approved.
  • Advanced detection: By interrogating genes for complex variants, we can identify the underlying causes of conditions that may otherwise be missed.

CLINICAL EXPERTISE

  • Thorough analysis: We classify variants according to our custom adaptation of the most recent guidelines. We then leverage our rich internal database for additional interpretation evidence.
  • Customized care: Our experts review all test results and write reports in a clear, concise, and personalized way. We also include information for research studies in specific clinical situations.
  • Impactful discovery: Our researchers continue working to find answers even after testing is complete. Through both internal research efforts and global collaborations, we have identified and published hundreds of new disease-gene relationships and developed novel tools for genomic data analysis. These efforts ultimately deliver more diagnostic findings to individuals.

Learn more About Us here.

Our Culture

At GeneDx, we are dedicated to cultivating an environment where creativity and innovation thrive. We believe in the power of community and collaboration, where diverse perspectives are embraced, and every voice contributes to our shared success. Our team is a vibrant mix of professionals who challenge and support each other in equal measure, fostering growth both personally and professionally. When you join us, you're not just taking on a job—you're joining a movement. A movement that champions curiosity, embraces change, and believes in making an impact, one patient at a time. Cultural principles we live by:  

  • Be bold in our vision & brave in our execution. 
  • Communicate directly, with empathy. 
  • Do what we say we're going to do.  
  • Be adaptable to change.  
  • Operate with a bias for action.    

Benefits include:

  • Paid Time Off (PTO)
  • Health, Dental, Vision and Life insurance
  • 401k Retirement Savings Plan
  • Employee Discounts
  • Voluntary benefits

GeneDx is an Equal Opportunity Employer.

All privacy policy information can be found here.

Average salary estimate

$180000 / YEARLY (est.)
min
max
$170000K
$190000K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

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At GeneDx, we believe that everyone deserves personalized, targeted medical care—and that it all begins with a genetic diagnosis

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Full-time, remote
DATE POSTED
May 20, 2025

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